Available	2025-09-04 – 2025-11-12
Contact person	Saskia Rughöft, employed at Lanekoff grupp

Please register here if you want to join the CML PhD Course with visiting Andrew Docker (Cambridge University).
This course is open to all interested PhD students and postdocs and will be geared towards those with a background in organic chemistry or supramolecular chemistry
or an interest in non-covalent interactions.
Registration deadline: November 12

Course title: Recognition, Assembly, and Function: Supramolecular Chemistry in the Chemical Mechanisms of Life
Course dates: December 1-5

Schedule:
Monday Dec 1: 13:30-16:00 Lecture 1
Tuesday Dec 2: 13:30-16:00 Lecture 2
Wednesday Dec 3: 13:30-16:00 Lecture 3
Thursday Dec 4: Time to work on the assignments
Friday Dec 5: 13:30-15:30 Seminar to discuss the assignment and any outstanding questions

Credits: 1.5
If you want to receive the credits, please make sure you can attend all course hours in person (or let us know in advance if not and explain the situation) and hand in the assignment on time. Please note: This is not a hybrid course.

Course content:
1. The Chemical Elements of Life: The biological toolbox
i) The ‘Natural Selection’ of the elements of chemical biology
ii) Biological Environment and Chemical Accessibility
iii) The Unique Chemistry of Hydrogen and Biology
iv) Periodic Table for the Elements of Life
v) Principles of Coordination Chemistry, Intermolecular Interactions and Molecular Recognition

2. Molecular Recognition in Biology: Biological Acquisition and Speciation of Inorganic Elements
i) Principles of Molecular Recognition: Stability, Preorganisation, Cooperativity and Selectivity
ii) Element Separation and Mechanisms of Compartmentalisation by Biological Systems
iii) Thermodynamic and Kinetic Control of Element Uptake
iv) Mechanisms of Achieving Selective Element Uptake, Storage and Transport

3. Supramolecular Self-Assembly in Biology: From Molecular Interactions to Functional Architectures
i) Principles of Self-Assembly: Thermodynamics, Kinetics, and Intermolecular Interactions
ii) Biological Architectures Built by Self-Assembly
iii) Metal- and Template-Directed Assembly in Nature
iv) Synthetic Mimics and Applications of Bio-inspired Self-Assembly